Human Kupffer Cells

product name：Human Kupffer Cells；

cat no：ABC-TC4369；

Size/Quantity：1 vial；

Biosafety Level：1；

Shipping Info：Dry Ice；

Storage：Liquid Nitrogen；

Description：Isolated and enriched from dissociated human liver tissue, Human Kupffer cells (HKC) are the resident macrophages in human liver. Kupffer cells are the densest innate liver immune cells and the first line of defense against bacteria and toxins in the intestine. Liver Kupffer cells have typical macrophages abilities like modulating hepatic inflammation and injury. Activated hepatic Kupffer cells could release inflammatory cytokines, growth factors and reactive oxygen species.

In vivo, the activation of Kupffer cells could mediate inflammation that develop into liver diseases such as Non-Alcoholic Fatty Liver Disease (NAFLD), Non-Alcoholic Steatohepatitis (NASH), and liver damage associated with certain bioactivated chemicals.；

Quality Control：All cells test negative for mycoplasma, bacteria, yeast, and fungi；

Application：For research use only.

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